TThe effect of uterine length measurement before embryo transfer versus transabdominal ultrasound-guided embryo transfer on FET cycles outcome: A Randomized Clinical Trial

Articles in Press

Document Type : Original Article

Authors

1 Research and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

2 Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

3 Research and Clinical Center for Infertility, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

10.22074/ijfs.2023.2000790.1460

Abstract

Background: Embryo transfer is an important step in assisted reproductive technology. Given that uterine length measurement before embryo transfer (ULMbET) enables determination of catheter length and anatomical variation before the embryo transfer, this study aimed to compare ULMbET and transabdominal ultrasound-guided embryo transfer (TAUGET).

Materials and Methods: In this open-label randomized clinical trial, 264 women who were scheduled for frozen-thawed embryo transfer cycles were randomized into two groups. Embryo transfer was done either using ULMbET or TAUGET methods. The primary outcome of this study was clinical pregnancy.

Results: One hundred and thirty-two women were randomized to the ULMbET group and 132 women to the TAUGET group. Four randomized women in ULMbET group did not receive the allocated method after randomization. Finally, 128 women were listed in ULMbET and 132 women in TAUGET groups. There were no statistically significant differences in chemical pregnancy rate (31.3% vs. 36.4%; P-value=0.38), clinical pregnancy rate (23.4% vs. 28%; P-value=0.39) and implantation rate (15% vs. 17.8%; P-value=0.40) between ULMbET and TAUGET groups respectively.

Conclusions: The results of this clinical trial showed that the pregnancy outcomes in frozen-thawed embryo transfer cycles following ULMbET and TAUGET were the same.

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International Journal of Fertility and Sterility

Articles in Press, Accepted Manuscript
Available Online from 25 September 2023

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