Validity and Reliability of the Persian Version of Uterine Fibroid Symptom and Health-related Quality of Life Questionnaire

Document Type : Original Article

Authors

1 Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

2 1. Preventative Gynecology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. Department of Cell & Molecular Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran

3 School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

10.22074/ijfs.2023.1988864.1431

Abstract

Objective: Women with Uterine Fibroid (UF) experience many clinical manifestations affecting their quality of life (QOL). Uterine Fibroid Symptom and Health-related Quality of Life (UFS-QOL) questionnaire is an English instrument that was specially designed to assess fibroid-related symptoms and their impact on the QOL. This study aimed to investigate the reliability and validity of the Persian- version of the UFS-QOL questionnaire in Iranian women with UFs.

Study Design: This study was carried out on women with UFs came to Imam Hossein hospital (Tehran, Iran) between august 2022 and January 2023. A forward-backward was applied to translate the UFS-QOL questionnaire into Persian. The reliability of the UFS-QOL questionnaire was assessed by internal consistency and test-retest correlation. Confirmatory factor analysis (CFA) was used to assess convergent validity between items and subscales of the UFS-QOL questionnaire. Also, Pearson's correlation coefficient was used to assess convergence validity between subscales of UFS-QOL and world health organization quality of life brief version (WHOQOL-BREF) 26 questionnaires.

Results: Overall, 226 women with UFs were analyzed in this study. All subscales of the UFS-QOL questionnaire had acceptable internal consistency (Cronbach's alpha > 0.7). Test-retest analysis indicated significant positive correlations between two measurements of all subscales of the UFS-QOL questionnaire: symptom severity (P<0.001), concern (P<0.001), activities (P<0.001), energy/mood (P<0.001), control (P<0.001), self-consciousness (P=0.002), and sexual function (P<0.001). The Kaiser-Meyer-Olkin (KMO) measure value was 0.920, and the result of Bartlett's test of sphericity was significant (P<0.001). CFA identified six factors for the health-related quality of life questionnaire, explaining 73.827% of the total variation. Furthermore, most subscales of the UFS-QOL questionnaire were correlated with domains of the WHOQOL-BREF questionnaire (P<0.05).

Conclusion: The Persian version of the UFS-QOL questionnaire is a valid and reliable instrument to evaluate UFs-related symptoms and QOL among Iranian women with UFs.

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Main Subjects

International Journal of Fertility and Sterility

Articles in Press, Accepted Manuscript
Available Online from 01 May 2023

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