Kidney Agenesis and Anomalies in Infertile Men with Congenital Absence of Vas Deferens (CAVD)

Document Type : Original Article

Authors

1 Department of Reproductive Imaging, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran

2 1. Department of Reproductive Imaging, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran

3 2. Department of Andrology, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran

Abstract

Background: The congenital vas deferens agenesis (CAVD), that has two forms of Congenital Bilateral Absence of the Vas deferens (CBAVD) and Congenital Unilateral Absence of the Vas deferens (CUAVD), is a rare anomaly in men. We aim at determining the prevalence of the renal anomalies in the patients with the congenital vas deferens agenesis referred for infertility assessment.
Materials and Methods: This cross_ sectional study was carried out on eligible infertile men from 2016 to 2019. A total of 125 infertile men who were suspected for obstructive azoospermia were referred to Ultrasound ward and they were examined by abdominal ultrasound for detecting the genital and kidney anomalies. The study and protocols were approved by the Institutional Ethics Committee. Patients were divided into two groups in terms of CBAVD or CUAVD. Using Chi- square test, kidney anomalies between groups were compared. P. value < 0.05% was considered significant.
Results: The mean age of participants was 33.05±6.35. Out of 125 referred patients, the CAVD was approved in 110 men. The frequency of CBAVD was 66 (52.8%) and the frequency of CUAVB was 44 (35.2%) (Left side CUAVB = 23, right side CUAVB = 21). The coexistence of the vas deferens and the kidney agenesis was seen in 12 men (11%). Although the percentage of kidney agenesis in the CBAVD and the CUAVD groups was 9.1% and 1.8%, respectively, the difference was not significant (P=0.07).
Conclusion: In CAVD cases, the renal agenesis should be ruled out with transabdominal ultrasound examination since it could not be detected by routine laboratory tests or transrectal ultrasound examination. Ultrasound examination is an accessible, safe and non-invasive method. If patients become aware of the unilateral kidney agenesis, they will take care of the remained kidney and look for the prognosis of their problem.

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