Correlation of Anti-Mullerian Hormone Level and Antral Follicle Count with Oocyte Number in A Fixed-Dose Controlled Ovarian Hyperstimulation of Patients of In Vitro Fertilization Program

Document Type : Original Article


Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran - Dr Hasan Sadikin Hospital (RSHS), Bandung, Indonesia


Background: This study was conducted to determine the correlation of anti-Mullerian hormone (AMH) level and
antral follicle count (AFC) with oocyte count in women who had received controlled ovarian hyperstimulation in an
in vitro fertilization (IVF) program.

Materials and Methods: We retrospectively gathered the data of 42 patients who underwent IVF during 2005-2017
at Aster Clinic in Dr. Hasan Sadikin Hospital and Bandung Fertility Center Limijati Hospital, Indonesia. Details of
the subjects such as identity, characteristics, history of illness, history of previous therapy, levels of ovarian reserve
markers examined (AFC and AMH), follicle-stimulating hormone (FSH) dose given, and number of oocytes produced
were recorded.

Results: A significant positive correlation between AMH (P≤0.001, r=0.530), AFC (P≤0.001, r=0.687), and AMHAFC
combination (P≤0.001, r=0.652), and the number of oocytes was found at the FSH dose of 225 IU.

Conclusion: AFC and AMH are able to reliably predict ovarian response to FSH.


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