Predictive Value of Endometrial Length Measurement by Transvaginal Ultrasound and IVF/ICSI Outcomes

Document Type : Original Article


1 Department of Reproductive Imaging, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran

2 Atherosclerosis Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran


Background: The purpose of this study to determine the relationship between endometrial length and positive pregnancy
test in patients who underwent assisted reproductive technology (ART).
Materials and Methods: 
This cross-sectional study included patients who were referred for in vitro fertilisation/intracytoplasmic
sperm injection (IVF/ICSI) therapy from 2013 to 2016. All nulliparous women who met the inclusion
criteria were between 20-38 years of age and presented for ultrasound measurements prior to fresh embryo transfer
(ET). Endometrial length was measured by transvaginal ultrasound (TVS) with a Medison Accuvix device on the day
of human chorionic gonadotropin (hCG) administration. The relationship between endometrial length and treatment
success was assessed. The independent sample t test, receiver operating characteristic (ROC) curve and the area under
the curve (AUC) index and chi-square test were used for data analysis. P values Results: There was a significant relationship between endometrial length (41.5%) and treatment success (p <0.05).
The endometrial length of 41.5(mm) with a sensitivity of 66.7%, specificity of 50.6%, positive predictive value of
46.8%, negative predictive value of 69.4%, and efficiency of 56.62% can be used as a proper cut-off point with an
AUC of 0.63.
Conclusion: The value of 41.5(mm) for endometrial length can be used as a proper cut-off point for prediction of a
higher ART success rate. We recommend TVS as the first step for assessment of uterine and endometrium receptivity
in the ART cycle.