The Effect of Body Mass Index on the Outcome of IVF/ICSI Cycles in Non Polycystic Ovary Syndrome Women

Moini, Ashraf; Amirchaghmaghi, Elham; Javidfar, Nafiseh; Shahrokh Tehraninejad, Ensieh; Sadeghi, Maria; Khafri, Soraya; Shabani, Fatemeh

doi:10.22074/ijfs.2008.45715

The Effect of Body Mass Index on the Outcome of IVF/ICSI Cycles in Non Polycystic Ovary Syndrome Women

Document Type : Original Article

Authors

10.22074/ijfs.2008.45715

Abstract

Background
The aim of this study was to investigate the effect of body mass index (BMI) on the outcome of in vitro fertilization (IVF)/ intracytoplasmic sperm injection (ICSI) cycles in non polycystic ovary syndrome (PCOs) women.

Materials and methods
In this cross sectional study, 287 infertile non PCOs women referred to Royan institute, Tehran, Iran between 2002 and 2003 were enrolled. Patients with age≥40 years old or BMI

Results
One hundred thirty three (46.3%) subjects had normal BMI, 117 women (40.8%) were overweight and 37 women (12.9%) were obese. Obese group had lower pregnancy rate (13.5%) in comparision to normal (29.3%) and overweight (21.4%) groups although this difference was not statistically significant (p=0.09). Chi square analysis showed that normal weight women had significantly higher regular mensturation (p=0.02). The logestic regression analysis showed that BMI significantly affects on pregnancy rate of ART cycles in non PCOs women (p=0.038).

Conclusion
The finding of this study suggested that in non PCOs women, BMI had independent adverse effect on the pregnancy rate of IVF/ICSI cycles.