Past Issue

Volume 7, Number 4, Jan-Mar 2014, Pages: 345-348

Nephrotic Sydrome Developing in Severe Ovarian Hyperstimulation Syndrome


Funda Gungor Ugurlucan, M.D, 1, *, Burcin Karamustafaoglu, M.D, 1, Ahmet Cem Iyibozkurt, M.D, 1, Isin Kilicaslan, Ph.D, 2, Yasar Caliskan, Ph.D, 3, Mehmet Ozsurmeli, M.D, 1, Ercan Bastu, M.D, 1, Faruk Buyru, M.D.Ph.D, 1,
Department of Obstetrics and Gynecology, Istanbul University, Istanbul Medical School, Istanbul, Turkey
Department of Pathology, Istanbul University, Istanbul Medical School, Istanbul, Turkey
Department of Internal Medicine, Division of Nephrology, Istanbul University, Istanbul Medical School, Istanbul, Turkey
* Corresponding Address: Department of Obstetrics and Gynecology Istanbul University Istanbul Medical School Istanbul-34156 Turkey Email: fgungor@yahoo.com

Abstract

We report a case that developed nephrotic syndrome during hospitalization for severe ovarian hyperstimulation syndrome without history of acute renal failure. During hospi- talization, she developed persistent ascites and respiratory distress. The 24 hours urine protein analysis revealed significant proteinuria and renal biopsy showed global and seg- mental sclerosis in glomeruli, mesangial arteritis, proliferations in visceral epithelial cells (IgA nephropathy). To the best of our knowledge, such a complication will be presented for the first time in the literature.