FABP9 Mutations Are Not Detected in Cases of
Infertility due to Sperm Morphological
Defects in Iranian Men
Fatty acid binding proteins (FABPs) are members of the intracellular li-
pid binding protein (iLBPs) family and most of them show tissue specific expression.
Materials and Methods:
In this case-control study, DNA was extracted from peripheral
blood of 100 infertile males with normal sperm count but with a number of morphologi-
cally abnormal sperms in their semen that was above normal. Four exons and one intron
We did not detect any mutation in any area of the four exons, intron 3 and splice
There was no mutation in the exonic regions and the poor sperm mor- phology. However, we didn’t analyze the promoter, intron 1 and 2 to establish conclusions regarding the association of these genic regions and sperm dysmor- phology.